Satiety signals are the body’s messages telling your brain you’re full, triggered by food in your stomach and nutrients in your blood, involving hormones like CCK, GLP-1, and PYY, plus stomach stretching, to stop eating and signal energy balance, ultimately integrating in the hypothalamus for appetite control. These signals work through nerves (like the vagus nerve) and hormones to tell the brain, especially the hindbrain and hypothalamus, that the meal is done and to regulate long-term energy, influencing meal size and frequency.

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