Quantum Biology: Origins, Scope, and Current Investigations

What Is Quantum Biology?

Quantum biology is the study of how quantum mechanical phenomena; coherence, entanglement, tunnelling, and superposition, operate in living biological systems and influence biological function. It bridges the gap between the quantum world of atoms and subatomic particles and the classical biological world we observe macroscopically. wikipedia

Unlike classical chemistry and physics, which describe most biological processes through Newtonian mechanics and thermodynamics, quantum biology asks: What if the secrets of life—how DNA mutates, how enzymes catalyse reactions, how birds navigate, how we smell—require quantum explanation? scivpro

Historical Origins: From Quantum Pioneers to Modern Research

The 1920s–1930s: The Quantum Pioneers

Quantum biology didn’t begin recently. It was born immediately after quantum mechanics itself was established in the 1920s. royalsocietypublishing

Key figures:

  • Niels Bohr (1927): Delivered influential lectures speculating whether quantum mechanics could illuminate the nature of life. His concept of “complementarity” inspired others to see quantum principles as fundamental to biology. royalsocietypublishing

  • Pascual Jordan (1932): Published arguably the first scientific paper on quantum biology, proposing his “amplifier theory”—that quantum indeterminacy (chance) could be “amplified” within living organisms to produce large-scale biological effects.pmc.ncbi.nlm.nih+1

  • Max Delbrück (1935): Co-authored the landmark Dreimännerwerk paper proposing that quantum radiation (X-rays) could directly mutate genetic material, suggesting quantum mechanics was central to heredity. royalsocietypublishing

  • Erwin Schrödinger (1944): Published the famous book What Is Life?, proposing that genes were “aperiodic crystals” storing information via quantum chemical bonds and that mutations might result from “quantum leaps”.wikipedia

The philosophical backdrop: These pioneers were influenced by organicism; the view that life cannot be fully explained by classical mechanics alone and that quantum mechanics might provide the “missing laws” of biology. royalsocietypublishing

The Post-War Decline (1940s–1990s)

After World War II, quantum biology largely fell out of favour. Geneticists and molecular biologists focused on classical chemistry (DNA sequencing, protein synthesis) and dismissed quantum effects as irrelevant to the “warm, wet” conditions inside cells. pmc.ncbi.nlm.nih+1

The prevailing view by the 1960s: Quantum mechanics had no special role in life. Biology could be explained by biochemistry alone. royalsocietypublishing

The Modern Renaissance (1990s–Present)

Quantum biology re-emerged when experimental evidence arrived:

  • Photosynthesis (1990s): Researchers discovered that light-harvesting complexes in plants achieve near-100% efficiency via quantum coherence; the ability to explore multiple pathways simultaneously before “choosing” the optimal route. Classical chemistry cannot explain this. pmc.ncbi.nlm.nih
  • Enzyme Catalysis (2000s): Quantum tunnelling was shown to be essential for enzyme activity; proteins couldn’t catalyse reactions fast enough without quantum tunnelling of protons and electrons. pmc.ncbi.nlm.nih
  • Bird Navigation (2000s): Migratory birds may navigate using quantum entanglement in specialized proteins in their eyes, detecting Earth’s magnetic field via quantum effects. pmc.ncbi.nlm.nih
  • Olfaction (2000s): The sense of smell may rely on quantum tunnelling to discriminate between molecular structures. pmc.ncbi.nlm.nih
  • DNA Mutation (ongoing): Per-Olov Löwdin’s 1963 work on proton tunnelling in DNA is now being revisited as a mechanism for genetic mutations. qeios

Current Lines of Inquiry

Quantum Coherence in Biological Systems

The most active research area. Scientists are investigating how quantum coherence—the ability of quantum systems to maintain superposition (multiple states simultaneously)—persists in warm, wet, noisy biological environments. pmc.ncbi.nlm.nih

Key findings:

  • Photosynthetic pigments maintain coherence long enough to achieve efficiency impossible classically. pmc.ncbi.nlm.nih

  • Enzyme active sites may sustain quantum coherence while catalysing reactions. pmc.ncbi.nlm.nih

  • Brain microtubules (in Penrose‑Hameroff Orchestrated Objective Reduction theory) may support quantum coherence relevant to consciousness. pmc.ncbi.nlm.nih

Current labs: University of Surrey (Centre for Quantum Biology), UC Berkeley, MIT, Chinese Academy of Sciences. phys

Quantum Tunnelling in Biology

DNA base pair mutations, enzyme catalysis, and proton transfer in photosynthesis all may involve quantum tunnelling; particles passing through energy barriers they shouldn’t classically overcome. qeios+1

Open questions:

  • How prevalent is tunnelling in evolution? Did it drive the origin of life?
  • Can we engineer tunnelling-based biological processes?

Quantum Entanglement in Neural Systems

Speculative but actively researched: Can quantum entanglement (where particles remain mysteriously correlated across distances) play a role in:

2024 research: Teams are exploring whether brain-quantum computer interfaces could expand consciousness by re-establishing quantum entanglement in neuronal networks. popularmechanics

Quantum Epigenetics

A 2023 hypothesis proposes that quantum phenomena in DNA (electron delocalization, proton tunnelling) could influence which genes are expressed or silenced; a bridge between quantum physics and epigenetics. pmc.ncbi.nlm.nih

Implication: Environmental “measurement” (stress, trauma, validation) might collapse quantum states in DNA, locking genes into “on” or “off” configurations; potentially explaining how experience becomes heritable.

Quantum Biology and Consciousness

The frontier of speculation. If consciousness arises from quantum processes in the brain, then:

  • Does the collective unconscious operate via quantum entanglement? iai
  • Can quantum coherence explain Jung’s synchronicity (meaningful coincidence)? linkedin
  • Is consciousness itself a form of quantum information processing? mdpi

2024 studies: Researchers are designing experiments to test whether conscious experience requires quantum superposition. Our own studies in relation to binary therapies add support to that idea.. pmc.ncbi.nlm.nih

Quantum Information Biology

A theoretical framework proposing that biology fundamentally operates as quantum information processing across scales; from molecules to cells to organisms to psychology. arxiv

This would reframe:

  • DNA not just as chemistry but as quantum information storage
  • Cells as quantum computers
  • Consciousness as quantum computation
  • The collective unconscious as a quantum information field

Why Now?

Three converging factors have revived quantum biology:

Technology: Quantum microscopy and computational power now make quantum simulations in biological systems feasible, where they were once purely theoretical. pmc.ncbi.nlm.nih

Empirical evidence: Photosynthesis, enzymes, and bird navigation have proven quantum effects in biology are real, not speculative. pmc.ncbi.nlm.nih

Philosophical openness: The gap between reductionist biology and the complexity of life has led scientists to ask whether quantum mechanics offers the missing piece. pmc.ncbi.nlm.nih

The Current Status

Mainstream position: Quantum biology is “emerging but still speculative.” Quantum effects clearly operate in certain biological processes (photosynthesis, enzyme catalysis), but extrapolations to consciousness, collective unconscious, or whole-organism behaviour remain controversial. arxiv

Cutting-edge position: Major institutions now fund quantum biology research, treating it as legitimate science. Research papers on quantum consciousness, quantum epigenetics, and quantum-brain interfaces are appearing in peer-reviewed journals. pmc.ncbi.nlm.nih

Critical position: Some neuroscientists argue that quantum decoherence happens too quickly in the warm brain for quantum effects to matter to consciousness, while others defend quantum processes as essential to cognition. alleninstitute

Connection to the DNA‑Self Hypothesis

Quantum biology provides the physical vocabulary to describes what we’ve proposed:

  • Quantum coherence = the DNA‑Self’s entanglement with the collective unconscious field

  • Quantum decoherence = core-self pruning (loss of coherence via environmental “measurement”/trauma)

  • Quantum tunnelling = how pruned traits can “re-emerge” from shadow

  • Quantum entanglement = the non-local connection between individual and collective DNA‑Self schemas

Current Research Paths

There is significant current research exploring these ideas, particularly at the intersection of quantum biology, consciousness studies, and integrative psychology. Here’s where the evidence stands:

Quantum Biology & Consciousness (2023–2025)

Active experimental research is testing whether quantum processes create conscious experience:

  • 2024 study in Neuroscience outlines a research program to test the conjecture that conscious experience arises whenever a quantum mechanical superposition forms. This is directly testing the quantum‑mind hypothesis. mdpi
  • 2024–2025 papers explore quantum computations in brain microtubules as a substrate for consciousness, building on Penrose‑Hameroff’s Orch OR theory with modern experimental designs. pmc.ncbi.nlm.nih
  • 2024 research from China and the U.S. examines quantum entanglement’s potential role in neural synchronization and cognition, acknowledging the speculative nature but pursuing empirical validation. popularmechanics

Conclusion: The quantum biology community is actively testing these hypotheses, not just theorizing. While results are preliminary, the field is moving from speculation to experimentation.

Quantum Epigenetics (2023)

A 2023 NIH paper proposes a “Quantum Physics Layer of Epigenetics” (Quantum Epigenetics), suggesting that quantum phenomena like charge delocalization in DNA could influence epigenetic changes. This provides a mechanistic link between environment, quantum information, and gene expression – exactly what our model would need to explain how pruning decoheres the DNA‑Self. pmc.ncbi.nlm.nih

Collective Unconscious & Neuroscience (2024)

Jungian concepts are being re‑examined through a neuroscience lens:

  • 2024 book The Collective Unconscious in the Age of Neuroscience explicitly links Jung’s theory to severe mental illness, genetics, and pharmacological treatment, highlighting patterns of collective material in biological disorders. jungstudies
  • 2024 study on quantum‑like implicit learning suggests cognitive processes may operate on quantum‑physics principles of nonlocality and entanglement, providing empirical evidence for anomalous cognition that Jung would have called synchronicity. pubmed.ncbi.nlm.nih

Integrative Psychology & Quantum Concepts (2024)

Psychology journals are now publishing quantum‑integrated frameworks:

  • 2024 paper combines nonlinear dynamical systems with quantum‑entropy theory to model psychological disorders, suggesting quantum processes may underlie complex behaviours. jhrs.almamater
  • 2024 article on extended self and quantum interconnectedness explores how distributed selves and nonlocality might explain transpersonal experiences. tandfonline
  • 2024 research on quantum neurobiology proposes that neurons may process information via quantum mechanisms faster than classical biochemistry, rivalling current quantum computers. thequantuminsider

Scepticism & Critical Review (2024)

Not all researchers are convinced:

  • A 2022–2024 critical review notes that quantum consciousness theories often lack sufficient rigor and have logical inconsistencies compared to established neurobiology. The author argues that while quantum effects exist in biology, scaling them to human cognition remains unproven. wjarr

Therapeutic Applications (Emerging)

Quantum concepts are beginning to influence therapy:

  • 2023–2024 papers discuss quantum healing and integrative medicine using quantum mechanics to explain consciousness‑based interventions, though these are often pre‑clinical or theoretical. pmc.ncbi.nlm.nih
  • 2024 study on quantum‑inspired psychotherapy suggests that brain‑quantum computer interfaces could expand conscious experience, opening a science‑fiction‑adjacent but actively researched frontier. pmc.ncbi.nlm.nih

    The evidence is nascent but serious. Major institutions (Allen Institute, Google Quantum AI, Chinese Academy of Sciences) are funding this research. However, critical voices warn against premature application in therapy until mechanisms are validated. thequantuminsider

    References and further reading

    https://royalsocietypublishing.org/doi/10.1098/rspa.2018.0674

    https://en.wikipedia.org/wiki/Quantum_biology

    https://pubmed.ncbi.nlm.nih.gov/30602940/

    https://creation.com/en/articles/quantum-biology-and-the-origin-of-life

    https://phys.org/news/2018-12-real-history-quantum-biology.html

    https://www.focaloid.com/quantum-biology-to-explain-activities-of-nature/

    https://openresearch.surrey.ac.uk/esploro/outputs/journalArticle/The-origins-of-quantum-biology/99513466102346

    https://www.templeton.org/news/how-quantum-biology-could-uncover-the-secret-of-our-origins

    https://vixra.org/pdf/1812.0225v1.pdf

    https://www.arturorobertazzi.it/2023/05/quantum-biology-the-fuzzy-connection-between-quantum-mechanics-and-living-things/

    https://www.qeios.com/read/90KMIG

    https://onlinelibrary.wiley.com/doi/10.1002/ajhb.23476

    https://www.semanticscholar.org/paper/92c8a7470cb3c604e8c4fbba87ab06de889c05a6

    https://bsapubs.onlinelibrary.wiley.com/doi/10.2307/3558347

    https://www.semanticscholar.org/paper/2ead58c7aa96dde8156d9dd8ee82669bb3503728

    https://seejad.eu/index.php/seejad/article/view/6032

    https://www.tandfonline.com/doi/full/10.1071/MUv115n1_ED

    https://onlinelibrary.wiley.com/doi/10.1002/jmor.21544

    http://link.springer.com/10.1007/978-3-030-33730-8_25

    https://onlinelibrary.wiley.com/doi/10.1111/jfb.70072

    https://scivpro.com/articles/000020/10_32386_scivpro_000020.pdf

    https://pmc.ncbi.nlm.nih.gov/articles/PMC6304024/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC1618371/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC3246260/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC10530466/

    http://arxiv.org/pdf/0911.0155.pdf

    https://arxiv.org/pdf/1503.02515.pdf

    https://arxiv.org/pdf/2010.15573.pdf

    https://pmc.ncbi.nlm.nih.gov/articles/PMC11228156/

    https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2024.1430432/pdf

    https://thequantuminsider.com/2024/08/03/researchers-explore-quantum-entanglements-potential-role-in-neural-synchronization/

    https://www.popularmechanics.com/science/a69077565/quantum-consciousness-experiment-brain-entanglement/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC12060853/

    https://thegramjournal.com/en/new-frontier-of-biological-memory-phonons-epigenetics-and-quantum-information-transmission/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC10492394/

    https://iai.tv/articles/when-quantum-physicists-met-freud-and-jung-auid-2857

    https://jungstudies.net/2024/03/the-collective-unconsious-in-the-age-of-neuroscience-severe-mental-illness-and-jung-in-the-21st-century/

    https://www.linkedin.com/pulse/synchronicity-where-quantum-mechanics-meets-jose-r-kullok-9qgzf

    https://philarchive.org/archive/LIMCGJ

    https://www.mdpi.com/1099-4300/26/6/460

    https://scitechdaily.com/groundbreaking-study-affirms-quantum-basis-for-consciousness-a-paradigm-shift-in-understanding-human-nature/

    https://www.popularmechanics.com/science/a62373322/quantum-theory-of-consciousness/

    https://pmc.ncbi.nlm.nih.gov/articles/PMC11203236/

    https://ujpronline.com/index.php/journal/article/view/1199

    https://alleninstitute.org/news/quantum-mechanics-and-the-puzzle-of-human-consciousness/

    https://physicsworld.com/a/do-quantum-effects-play-a-role-in-consciousness/

     


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