Over-diagnosis

Over-diagnosis” by DES Daughter is licensed under CC BY-NC-SA 2.0

Overdiagnosis of Schizophrenia:

Evidence of Diagnostic Shortfalls in Hospitals

You may be surprised to learn that a great many schizophrenia diagnoses in hospitals often occur without comprehensive psychological assessments, relying instead on symptom checklists amid high-stakes inpatient pressures, leading to frequent mislabelling and resulting in misdiagnosis. sciencedaily

Key Studies on Misdiagnosis

Johns Hopkins EPIC Clinic (2011-2017) reviewed 54 referrals with schizophrenia diagnoses: 51% were re-diagnosed as anxiety/mood disorders after 3-4 hour evaluations including interviews, exams, and histories. Auditory hallucinations and anxiety were primary misdiagnosis drivers. sciencedaily

Russian analysis highlights “sluggish schizophrenia” overdiagnosis via cognitive biases like false consensus and preconceptions, affecting ~24-39% of cases; retrospective reviews overturn half upon specialist reassessment. journals.eco-vector+1

Leading psychiatrists achieved only 33% accuracy on schizophrenia patient reviews, underscoring the fact that even experts can be highly unreliable without structured tools and clear common understandings of symptomology. onlinelibrary.wiley

Diagnostic Process Gaps

No single test exists for Schizophrenia: DSM-5 requires ruling out substances/medical causes via history/exams, yet hospital protocols prioritize rapid patient reviews over in-depth psychometric testing and analysis. (e.g., PANSS, MINI). “Checklist psychiatry” in EHRs exacerbates errors. pmc.ncbi.nlm.nih

Issue Prevalence Consequence qualitysafety.bmj
Initial Schizophrenia → Anxiety/Mood 36-51% Inappropriate antipsychotics, delayed therapy.
First-Rank Symptoms Alone 75-95% sensitivity, but 5-19% false positives Triage errors miss ~40% true cases.
Personality Disorder Mislabel ~24% Stigmatization, unnecessary hospitalization.

The Rosenhan Experiment

Sane Pseudo patients Labelled Schizophrenic

There was also research where known non-schizophrenics attended Emergency Rooms to seek advice on hearing voices. They were admitted to hospital for observation, did not “hear” voices at all in hospital, but still got the diagnosis.

The landmark 1973 Rosenhan experiment (“On Being Sane in Insane Places”) directly demonstrated this: Eight mentally healthy pseudo patients feigned auditory hallucinations to seek admission, then ceased symptoms and behaved normally, yet received schizophrenia diagnoses. wikipedia

Experiment Details

Pseudo patients (including Rosenhan) phoned 12 U.S. hospitals claiming voices saying “empty,” “hollow,” “thud.” All admitted (11 were diagnosed with schizophrenia, and 1 with manic-depression); their average stay was 19 days (7-52).

Post-admission, they reported feeling fine, no voices; normal conduct (e.g., note-taking labelled “writing behaviour”). Staff detected zero imposters; other patients suspected as being misdiagnosed counted for 35 out of 210 cases. simplypsychology

Discharge required them having to agree with having “schizophrenia in remission”, and were prescribed antipsychotics (flushed).wikipedia

Follow-Up Phase

One hospital, warned of pseudo patients in advance, decided that out of 193 admissions,  41 were found “likely” and 23 “suspect” to be fakes. Yet, none were sent, exposing labelling bias. velvetshark

Although, when reported to the world of psychiatry, the science claimed shock, and pushed forward a number of reforms to the industries diagnostic handbook, DSM-III: Reliability reforms and attempts to promote deinstitutionalization seems to have failed to have any lasting impact of this, potentially global propensity for overdiagnosis and misdiagnosis.

Implications and Reforms

Overdiagnosis fuels stigma, medication side effects, and costs; second opinions at specialty clinics are recommended. Multimodal technology (EEG, video), also shows promise for objective assessments. pmc.ncbi.nlm.nih

Limitations Persist

Multi-site studies following the updates to DSM-III still show 20-50% misdiagnosis rates. onlinelibrary.wiley

​This seems to point towards continued misunderstanding, confusion and denial of a shared conceptual model of how schizoid disorders work. It may also point to a social/organisational imbalance, impacting an individuals freedom of expression. The idea, that some ways of thinking, may, in themselves be seen as dangerous enough to warrant a diagnosis, regardless of the understood symptoms.

DSM reforms post-Rosenhan may have improved reliability, in theory, but but the suggestion is that entrenched biomedical checklists, tend to pathologize  divergent cognition (e.g., “magical thinking” flags schizotypal) as threats to an individual self-concept, rather than an understandable, perhaps eccentric, symptomizing alternative forms of expression. wikipedia

Calls for Change

Campaigners and anti-psychiatry advocates have long criticized schizophrenia diagnosis as overused, racially biased, and pathologizing normal distress or cultural expressions, leading to misdiagnosis of Black individuals and coercive treatment.

R.D. Laing (Anti-Psychiatry Pioneer): Argued that schizophrenia is not an illness but an existential response to family and societal madness. InThe Divided Self (1960, p. 120),Laing write,  “The schizophrenic is responding to something real.”. In the book, they challenge the idea of diagnosis, claiming that it was labelling authentic symbolic distress as brain disease. wikipedia

Thomas Szasz (Anti-Psychiatrist): Called “Mental illness” an incoherence in relation to schizophrenia, and that it was more of a deviance from norms, which can even include spiritual views, that cause society to lobby for their suppression, often via diagnosis and medication.
Szasz wrote, in The Myth of Mental Illness (1961, p. 119), “Schizophrenia has no physical cause… that is a myth.” He calls the diagnosis and related medication a form of social control, not any real concern over the individuals health. pmc.ncbi.nlm.nih

Jonathan Metzl (Protest Psychosis Author): Claimed that 1960s psychiatry labelled Black civil rights anger “schizophrenia.”. In The Protest Psychosis (2010), he said “schizophrenia became a Black disease” and claimed it to be a racial bias, applied to suppress black people, to imprison them, without any need to break laws. Black patients are four times more likely to be diagnosed with schizophrenia. pmc.ncbi.nlm.nih

Mad Pride/Survivor Activists (MindFreedom International): Are an organisation that reject labels, and demand non-medical support for individuals in psychosis., claiming, ““Madness is an aspect of my identity—who I am and how I experience the world—not an ‘illness’ that is separate from me.” The Identity of Psychiatry and the Challenge of Mad Activism. PMC7703744, pp.20-21.
The organisation claims that overdiagnosis ignores trauma/spiritual experiences and labels them “schizophrenia.” vice

References

Laing, R.D. (1960). The Divided Self. Penguin. p.120.

Szasz, T.S. (1961). The Myth of Mental Illness. Harper. p.119.

Metzl, J. (2010). The Protest Psychosis. Beacon Press.

MindFreedom International Statements (2000s).

Campaigners demand depathologization, cultural diagnostics, and an end to coercive antipsychotics.

Further Reading

https://en.wikipedia.org/wiki/Anti-psychiatry

https://pmc.ncbi.nlm.nih.gov/articles/PMC5353517/

https://pmc.ncbi.nlm.nih.gov/articles/PMC9947477/

https://www.psychologytoday.com/gb/blog/side-effects/201005/how-schizophrenia-became-black-disease-interview-jonathan-metzl

https://www.voiceability.org/news/the-protest-psychosis-how-schizophrenia-became-a-black-disease

https://pmc.ncbi.nlm.nih.gov/articles/PMC7703744/

https://www.vice.com/en/article/the-movement-against-psychiatry/

https://www.semanticscholar.org/paper/3d8f087155823cce284cce3e47552008946829bb

https://www.cambridge.org/core/product/identifier/S0924270815000150/type/journal_article

https://www.semanticscholar.org/paper/d86516fb880d72a9a23009540445c4bb13878db4

https://philmed.pitt.edu/philmed/article/download/19/17

https://www.cambridge.org/core/services/aop-cambridge-core/content/view/277BA5E0C47221237EA2E0ED3D1EF45D/S1092852924000543a.pdf/div-class-title-failure-to-treat-an-american-policy-perspective-div.pdf

https://pmc.ncbi.nlm.nih.gov/articles/PMC10599132/

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.663985/pdf

https://pmc.ncbi.nlm.nih.gov/articles/PMC3665855/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11629340/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4002061/

https://pmc.ncbi.nlm.nih.gov/articles/PMC8245788/

https://www.ucl.ac.uk/news/2025/mar/opinion-are-mental-health-conditions-overdiagnosed-uk

https://www.mind.org.uk/about-us/our-policy-work/the-big-mental-health-report/

https://www.newstatesman.com/spotlight/healthcare/mental-health/2025/05/symposium-are-we-over-diagnosing-mental-health-conditions

https://www.sciencedirect.com/science/article/pii/S2666560324000471

https://www.madinamerica.com/2017/01/researcher-acknowledges-mistakes-understanding-schizophrenia/

https://journals.sagepub.com/doi/10.1177/00957984221135377

https://jacobin.com/2022/03/anti-psychiatry-movement-mental-illness-psychological-suffering

https://www.rcpsych.ac.uk/news-and-features/latest-news/detail/2024/05/21/discrimination-against-people-with-severe-mental-illness-is-cutting-lives-short—-uk-s-top-psychiatrist

https://psychcentral.com/schizophrenia/quotes-on-living-with-schizophrenia

https://academic.oup.com/book/25012/chapter/189023517

https://www.goodreads.com/work/quotes/56276422-the-collected-schizophrenias-essays

https://www.bbc.co.uk/bbcthree/article/df13daea-9aa8-4956-8cd1-e28076210fbf

https://www.facebook.com/groups/165563067224915/posts/1111497182631494/

https://en.wikipedia.org/wiki/Rosenhan_experiment

https://qualitysafety.bmj.com/content/33/10/663

https://www.sciencedaily.com/releases/2019/04/190422090842.htm

https://onlinelibrary.wiley.com/doi/10.1111/pcn.13864

https://www.nature.com/articles/d41586-019-03268-y

https://journals.eco-vector.com/1027-4898/article/view/160308

https://pmc.ncbi.nlm.nih.gov/articles/PMC4472377/

https://en.wikipedia.org/wiki/Rosenhan_experiment

https://www.psychiatriapolska.pl/The-fiftieth-anniversary-of-the-article-that-shook-up-psychiatry,155398,0,2.html

https://www.nature.com/articles/d41586-019-03268-y

https://onlinelibrary.wiley.com/doi/10.1111/pcn.13864

https://www.sciencedaily.com/releases/2019/04/190422090842.htm

https://www.sciencedaily.com/releases/2019/04/190422090842.htm

https://journals.eco-vector.com/1027-4898/article/view/160308

https://qualitysafety.bmj.com/content/33/10/663

https://onlinelibrary.wiley.com/doi/10.1111/pcn.13864

https://pmc.ncbi.nlm.nih.gov/articles/PMC5593247/

https://www.nhs.uk/mental-health/conditions/schizophrenia/diagnosis/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11510732/

https://pmc.ncbi.nlm.nih.gov/articles/PMC4472377/

https://www.dovepress.com/efficacy-of-psychosocial-and-psychological-interventions-in-addition-t-peer-reviewed-fulltext-article-NDT

https://www.cambridge.org/core/product/identifier/S0007125023001289/type/journal_article

https://journals.sagepub.com/doi/10.1177/0020764017725770

https://onlinelibrary.wiley.com/doi/10.1002/mpr.1595

https://www.frontiersin.org/articles/10.3389/fpsyt.2022.809807/full

https://link.springer.com/10.1007/s00406-023-01560-7

https://www.frontiersin.org/articles/10.3389/fpsyt.2021.661174/full

https://www.mdpi.com/1424-8247/17/4/535

https://academic.oup.com/schizophreniabulletin/article-lookup/doi/10.1093/schbul/2.2.266

https://pmc.ncbi.nlm.nih.gov/articles/PMC9347514/

https://pmc.ncbi.nlm.nih.gov/articles/PMC7079421/

https://pmc.ncbi.nlm.nih.gov/articles/PMC3048511/

https://pmc.ncbi.nlm.nih.gov/articles/PMC10754154/

https://pmc.ncbi.nlm.nih.gov/articles/PMC9330209/

https://pmc.ncbi.nlm.nih.gov/articles/PMC11048323/

https://www.mayoclinic.org/diseases-conditions/schizophrenia/diagnosis-treatment/drc-20354449

https://111.wales.nhs.uk/Encyclopaedia/s/article/schizophrenia/

https://www.webmd.com/schizophrenia/diagnostic-tests-schizophrenia

https://nyulangone.org/conditions/schizophrenia/diagnosis

https://pmc.ncbi.nlm.nih.gov/articles/PMC5119925/

https://www2.hse.ie/conditions/schizophrenia/diagnosis/

https://www.cambridge.org/core/journals/epidemiology-and-psychiatric-sciences/article/is-there-a-mental-health-diagnostic-crisis-in-primary-care-current-research-practices-in-global-mental-health-cannot-answer-that-question/E1D728D06EC77A98D799DBC612600021

https://www.rcpsych.ac.uk/mental-health/mental-illnesses-and-mental-health-problems/schizophrenia

https://pubmed.ncbi.nlm.nih.gov/11129303/

https://slam.nhs.uk/schizophrenia

https://pmc.ncbi.nlm.nih.gov/articles/PMC6161382/

https://www.sciencedirect.com/science/article/abs/pii/S0924933817328997

https://www.nhs.uk/mental-health/conditions/psychosis/diagnosis/

https://www.clinicaltrialsarena.com/analyst-comment/schizophrenia-cases-undiagnosed/

https://journals.sagepub.com/doi/10.1177/000486740003401S25

https://pmc.ncbi.nlm.nih.gov/articles/PMC5103459/


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