tricyclic antidepressants are a class of drugs that treat depression and some other mental disorders. They work by increasing the levels of certain neurotransmitters, such as serotonin and norepinephrine, in the brain. These chemicals help regulate mood, sleep, and pain. tricyclic antidepressants have more side effects than newer antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), and are usually prescribed when other treatments have failed.

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